The 2025 Nobel Prize in Physiology or Medicine has been awarded to three scientists for their groundbreaking work on the functions of the immune system.
The laureates include two Americans, Mary Barnew and Frederms Dell, and one Japanese, Saka Guchi.
These scientists discovered how the immune system protects humans from thousands of different pathogens. According to a statement from the Nobel Committee, their research revealed fundamental insights into adaptive immune tolerance, helping us understand how the immune system works and why we do not suffer from all severe autoimmune diseases.
Saka Guchi, a Japanese immunologist, first discovered new T-cells in 1995, demonstrating that the immune system is far more complex than previously thought.
Building on Guchi’s discovery, Mary Barnew and Frederms Dell extended the research in the 2000s, further exploring the intricate mechanisms of immune function.
Their combined work has provided crucial knowledge for immunology and opened new avenues for understanding and treating immune-related diseases.
